Resveratrol Enhances the Radiosensitivity by Inducing DNA Damage and Antitumor Immunity in a Glioblastoma Rat Model under 3 T MRI Monitoring

Figure 4

The effects of radiation and resveratrol on apoptosis and cell cycle of tumor tissues in GBM rats (a) TUNEL staining was applied to examine apoptosis of brain tissue. Magnification ×200,  μm. Data are expressed as , . ^▲▲ vs. normal control; vs. radiation; ^&& vs. resveratrol. (b) The roles of radiation and resveratrol on the distribution of cell cycle were examined by flow cytometry. Data are expressed as , . ^▲ and ^▲▲ vs. normal control; ^& vs. resveratrol; vs. radiation. (c) The roles of radiation and resveratrol on cell cycle- and apoptosis-related factors assessed by Western blot. Data are expressed as , . ^▲ and ^▲▲ vs. normal control; and vs. radiation; ^& and ^&& vs. resveratrol.

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