|
| | Inclusion criteria | Exclusion criteria |
|
| 1. | Colorectal cancer patients with unresectable liver metastases | Weight loss >10% in the last 6 months. |
| 2. | Histological indications of adenocarcinoma in a surgically excised primary tumour | Hypersensitivity to rapamycin is reported. |
| 3. | Within 12 months of the faculty meeting at the transplantation unit, there were no symptoms of tumour recurrence as determined by colonoscopy/CT colography. | Largest liver metastasis >10 cm |
| 4. | Within 4 weeks of the faculty meeting at the transplant unit, there were no symptoms of extrahepatic metastatic disease or local recurrence on CT or MRI (thorax/abdomen/pelvis). | Other cancers that have not been cured |
| 5. | ECOG grade 0 or 1 indicates good performance. | Patient BMI>30 kg/m2 |
| 6. | Patients at least 18 years of age | Any reason why the patient should not participate, in the investigator's judgement |
| 7. | For patients with rectal cancer, a standard surgical approach with appropriate resection margins and a CRM of at least 2 mm is recommended. | Pregnant or breastfeeding women |
| 8. | According to good clinical practise and national/local legislation, signed informed consent and the patient's expected cooperation for treatment and follow-up must be obtained and documented. | — |
| 9. | According to PET/CT, there is no evidence of extrahepatic metastatic disease or local recurrence. | — |
| 10. | The patient might be included even if he or she does not need any further chemotherapy. According to RECIST 1.1, if chemotherapy is used, the patient should have a response or stable illness. | — |
|
