A Machine Learning Workflow of Multiplexed Immunofluorescence Images to Interrogate Activator and Tolerogenic Profiles of Conventional Type 1 Dendritic Cells Infiltrating Melanomas of Disease-Free and Metastatic Patients

Table 1

Clinical information of the study cohort.

No.	Patient code	Classification	T	N	M	Breslow (mm)	Histologic type	Clinic evolution
1	5532	MT	T4B	1B	0	7	Acral lentiginous	Regional metastases, progression to lung, liver and, mediastinum, and abdominopelvic invasion (local and distant)
2	2847	MT	T4B	NR	IB	12	Nodular	Central nervous system, lung, and liver metastases (distant)
3	4563	MT	T4B	3C	0	13	Acral lentiginous	Lymph node metastases (local)
4	7737	MT	T4B	1	0	11	Spindle cell	Lung and liver metastases (distant)
5	5539	MT	T4B	3C	0	4	Acral lentiginous	Inguinal activity with multiple satellite lesions (local)
6	9337	MT	T4B	1	0	23	Nodular	Regional metastases (local)
7	5406	DF	2	0	0	2	Superficial spreading	Remission
8	2126	DF	1	0	0	0.8	Acral lentiginous	Remission
9	2242	DF	T1A	0	0	0.3	Acral lentiginous	Remission
10	5835	DF	T3	0	0	3	Superficial spreading	Remission
11	1009	DF	2	0	0	1.1	Acral lentiginous	Remission
12	8011	DF	4	1	0	4	Nodular	Remission
13	5017	DF	1	0	0	0.6	Acral lentiginous	Remission
14	6321	DF	TIS	0	0	NA	Acral lentiginous	Remission
15	9242	DF	T4B	0	0	12	Nodular	Remission
16	4953	DF	T3B	0	0	2.2	Nodular	Remission
17	8464	DF	TIS	0	0	NA	Acral lentiginous	Remission

TNM classification: T: tumor, N: node, M: metastases (also MT in classification), NA: no applicable.