Tumor Suppressor Role of INPP4B in Chemoresistant Retinoblastoma

<div>Impact of lentiviral INPP4B upregulation in etoposide resistant RB (etop) cells on tumor formation in CAM assays. (a) The left photo panel depicts CAM tumors <i>in ovo</i>, and the right panel measuring (in cm) of excised tumors. <i>In vivo</i> CAM assays revealed that tumors forming from INPP4B overexpressing (OE), etoposide resistant (Etop) Y79, and RB355 cells were smaller than those developing from control cells (ctr). (b–d) Graphical evaluation of CAM tumor weight (b), size (c), and tumor formation capacity (d). 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and experimental groups.</div>

Journal of Oncology

Tumor Suppressor Role of INPP4B in Chemoresistant Retinoblastoma

Figure 6