Deciphering the Molecular Mechanism of Yifei-Sanjie Pill in Cancer-Related Fatigue

Figure 5

Quercetin is an active component of YFSJ acting on the Stat3-related signaling pathway. (a) Total ion current profiles for identification of natural products in samples (black is the total ion current diagram in negative ion mode and red is the total ion current diagram in positive ion mode). (b) The information of the compound (quercetin) obtained by matching the LC/MS map with the database. (c) The 3D structure of quercetin. (d) The 3D structure and phosphorylation site of Stat3 protein. (e) Molecular docking mode prediction of quercetin and Stat3 and its “affinity” and “RMSD.”

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