Research Article
OLFML2A Overexpression Predicts an Unfavorable Prognosis in Patients with AML
Table 2
Logistic analysis of the relationship between OLFML2A expression and the clinicopathological features in the TCGA-AML database
| | Characteristics | Total (N) | Odds ratio (OLFML2A) | value |
| | Gender (male vs. female) | 151 | 1.024 (0.539–1.948) | 0.941 | | Race (White vs. Asian and Black or African American) | 149 | 0.761 (0.239–2.305) | 0.630 | | Age (>60 vs. ≤60) | 151 | 1.600 (0.836–3.090) | 0.158 | | WBC count (×10^9/L) (>20 vs. ≤20) | 150 | 1.620 (0.853–3.106) | 0.142 | | BM blasts (%) (>20 vs. ≤20) | 151 | 0.733 (0.379–1.408) | 0.352 | | PB blasts (%) (>70 vs. ≤70) | 151 | 1.412 (0.745–2.692) | 0.292 | | Cytogenetic risk (intermediate and poor vs. favorable) | 149 | 2.575 (1.140–6.156) | 0.027 | | FAB classifications (M1&M2&M3&M4&M5&M6&M7 vs. M0) | 150 | 0.657 (0.210–1.923) | 0.448 | | Cytogenetics (+8&del (5) &del (7) &inv (16) &t (15; 17) &t (8; 21) &t (9; 11) &complex vs. normal) | 135 | 0.814 (0.413–1.600) | 0.551 | | FLT3 mutation (positive vs. negative) | 147 | 3.038 (1.467–6.541) | 0.003 | | IDH1 R132 mutation (positive vs. Negative) | 149 | 0.607 (0.176–1.912) | 0.402 | | IDH1 R140 mutation (positive vs. negative) | 149 | 0.684 (0.194–2.245) | 0.533 | | RAS mutation (positive vs. negative) | 150 | 1.000 (0.228–4.378) | 1.000 | | NPM1 mutation (positive vs. negative) | 150 | 1.081 (0.498–2.357) | 0.844 |
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