ADRB2 Regulates the Proliferation and Metastasis of Gastrointestinal Stromal Tumor Cells by Enhancing the ETV1-c-KIT Signaling

Figure 1

High ADRB2 expression is associated with prognosis in patients with gastrointestinal stromal tumors. (a) Kaplan–Meier disease-free survival curves for 122 patients with gastrointestinal stromal tumor stratified by high and low expression of ADRB2. (b) Real-time PCR was used to detect the mRNA levels of ADRB2 in high immunoreactivity-score group compared to low immunoreactivity-score group. (c–f) The mRNA levels of ADRB2 correlate with risk level, tumor size, mitotic count and liver metastasis. (g) Representative staining of ADRB2 and c-KIT in GIST tissues. Magnification: 400×; ^∗∗∗ < 0.001.

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