LncRNA CASC2 Regulate Cell Proliferation and Invasion by Targeting miR-155/SOCS1 Axis in Hepatocellular Carcinoma

Table 1

Univariate and multivariate analyses for correlation of CASC2 expression with OS of HCC patients.

Variable	Univariate Cox’s regression analysis		Multivariate Cox’s regression analysis
	Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
CASC2 expression (high vs. low)	1.237 (0.775–2.044)	0.008	1.879 (0.711–2.425)	0.004
Sex (male vs. female)	2.432 (1.337–3.212)	0.304	—	—
Age (<60 years vs. ≥60 years)	2.099 (1.225–3.108)	0.112	—	—
Tumor size (≥5 cm vs. <5 cm)	0.974 (0.582–1.706)	0.284	—	—
TNM staging (I∼II vs. III∼IV)	1.262 (0.897–1.981)	0.016	1.765 (0.892–2.241)	0.012
Differentiation (poor vs. good/moderate)	1.417 (0.692–2.288)	0.492	—	—
Lymph node metastasis (yes vs. No)	1.696 (1.125–2.198)	0.005	1.233 (1.108–2.491)	0.002

value was acquired by Cox proportional hazards regression. Statistically significant ().