Identification and Validation of a m5C RNA Modification-Related Gene Signature for Predicting Prognosis and Immunotherapeutic Efficiency of Gastric Cancer

Figure 2

Construction of an m5C-related risk model. (a) The volcano map of DEGs of two subtypes of survival differences in GC. The abscissa represents log2^FC, and the ordinate represents −log10 (adjust. value). Red: upregulation; blue: downregulation. (a) The volcano map of DEGs between GC and normal samples from the TCGA database. Red: upregulation; blue: downregulation. (c) The heat map of DEGs of two subtypes. (d) The heat map of DEGs between normal and GC samples. (e) The venn diagram of DEGs in (a) and (b). (f) Screening characteristic genes by LASSO regression analysis. The abscissa is log (Lambda), and the ordinate is the coefficient of the gene. (g) The KM survival curve of high-andlow-risk groups in the training set. (h) The ROC curve and AUC for four DEm5CRGs.

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