Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model

Table 2

Morphologic evaluation of glomerular sclerosis and tubulointerstitial fibrosis at the end of study.

	WKY	MC/MF	HC/LF
Glomerular sclerosis score	$0.13\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.02$	$0.63\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.03$ ***	$0.43\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.02$^***†††
Tubulointerstitial fibrosis (%)	$1.8\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.1$	$4.6\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.3$ ***	$3.3\mathrm{\hspace{0.17em}\hspace{0.17em}}\pm \mathrm{\hspace{0.17em}\hspace{0.17em}}0.4$^*†

* $P<.05$, ***$P<.001$ versus WKY; ^†$P<.05\text{,}$^†††$P<.001$ versus MC/MF.