Journal of Obesity / 2010 / Article / Tab 1 / Research Article
Feeding Regulates the Expression of Pancreatic Genes in Gastric Mucosa Table 1 Transcripts coding for digestive and secretory proteins differentially modulated by feeding in the gastric mucosa.
Tag Fasting Low fat High fat Description 30 min 1 h 3 h 30 min 1 h 3 h Digestive enzymes CTGACTCAAAA 713 86 ↓ 48 ↓ 2020 ↑ 383
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106 ↓ 70 ↓
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Amylase 2a1, pancreatic (Mm.439729; NM_001042712) CCCTGGGTTCA 130 4 ↓ 2 ↓ 353 ↑ 72
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14 ↓ 0 ↓
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Chymotrypsinogen B1 (Mm.34374; BC061083) TTAGGAGGCTG 164 11 ↓ 6 ↓ 346 72
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12 ↓ 2 ↓
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Pancreatic lipase (Mm.20407; NM_026925) GGCTGTAATGT 65 6 ↓ 6 ↓ 175 52
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8 ↓ 7 ↓
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Elastase 1, pancreatic (Mm.2131; NM_033612) GTGTGCGCCGG 61 4 ↓ 2 ↓ 117 32 2 ↓ 0 ↓
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Elastase 3, pancreatic (Mm.297477; BC061066) TTCTGTCTGGG 51 0 ↓ 6 ↓ 102 18 2 ↓ 0 ↓
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Trypsinogen 7 ( RIKEN cDNA 2210010C04 gene; CCCGGGTGCAA 0 4 4 36 ↑ 8 0 2
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Pancreatic lipase related protein 1 (Mm.10753; BC068266). GACCACACTGT 35 6 0 ↓ 109 28 10 0 ↓
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Carboxypeptidase A1 (Mm.25377; BC052661) GAGCACGTACG 14 0 0 36 4 0 0
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Carboxypeptidase A2, pancreatic (Mm.268855; NM_001024698) ATCTGTGTTGG 193 27 ↓ 31 ↓ 317 68 37 ↓ 25 ↓
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Protease serine 2 (Mm.276926; NM_009430)/Trypsin 4 (Mm.383263; NM_011646) GCCTACAACTA 30 0 ↓ 4 113 ↑ 16 2 ↓ 0 ↓
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Chymotrypsin-like (Mm.2745; NM_023182) GCACCAAGTAC 26 0 ↓ 0 ↓ 98 ↑ 16 2 2
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EST Carboxypeptidase B1 (Mm.34692; CF577795) CAGACTAAGTA 24 4 2 122 ↑ 26 0 ↓ 2 Carboxyl ester lipase (Mm.236017; NM_009885) Exocytosis/secretory GCAAGACCCGC 26 2 0 ↓ 49 16 2 5
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Syncollin (Mm.25210; NM_026716) AAAGTATGCAA 122 25 ↓ 37 ↓ 98 72 37 ↓ 34 ↓ Zymogen granule membrane protein 16 (RIKEN cDNA 1810010M01 gene; Mm.21835; BC031800)
Numbers indicate the count of serial analysis of gene expression (SAGE) tags per 50000.↓ indicate a significant differential regulation by LF or HF feeding compared to fasting (
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