Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy

Table 1

General and biochemical characteristics of obese patients and control subjects.

	Obese patients	Control subjects
	(𝑛=100)	(𝑛=100)
Females (%)	60	64
Age (years)	32.1±10.9	33.3±8.1
BMI* (kg/m^2)	47.9±6.9	22.8±2.1
Adiponectin* (𝜇g/mL)	31.6±30.0	53.8±38.6
Leptin* (ng/mL)	119.6±72.4	21.9±18.7
Resistin (ng/mL)	12.2±8.4	12.7±7.9
Glucose* (mmol/L)	4.9±0.8	4.5±0.4
Total cholesterol (mmol/L)	4.7±1.1	5.0±0.7
Triacylglycerols* (mmol/L)	1.5±0.6	0.9±0.3
AST* (U/L)	26.5±16.7	19.8±5.6
ALT* (U/L)	39.8±35.0	22.5±12.9
GGT* (U/L)	35.3±26.0	17.4±10.4
Creatinine (mg/dL)	0.9±0.2	0.7±0.1

*Statistically significant difference between obese and control subjects, 𝑃<.001 at Mann-Whitney test. Biochemical parameters were measured by routine laboratory methods. Adipokines concentrations were measured by ELISA assay (LINCO Research, Mo, USA). Values are expressed as mean ± SD.