Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier

Table 2

Associations of SNPs in FTO and MC4R genes with age, sex adjusted Z scores of obesity traits.

	rs9939609				rs17782313
	𝑁	Coeff^a	95% CI	𝑃	𝑁	Coeff^a	95% CI	𝑃
BMI	6170	0.08	(0.02, 0.14)	.009	6240	0.04	(−0.01, 0.10)	.14
WHR	6160	0.01	(−0.05, 0.07)	.77	6230	−0.01	(−0.07, 0.05)	.75
Waist circumference	6160	0.04	(−0.02, 0.11)	.16	6230	0.04	(−0.02, 0.10)	.22
Weight	6170	0.09	(0.03, 0.15)	.003	6240	0.06	(0.001, 0.12)	.045
Hip circumference	6168	0.05	(−0.01, 0.11)	.08	6238	0.06	(0.01, 0.12)	.03
Body fat	5968	0.02	(−0.04, 0.08)	.57	6028	0.05	(−0.01, 0.11)	.08

BMI, body mass index; WHR, waist-hip ratio
^aCoefficents represent SD change per minor allele.