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Journal of Obesity
Volume 2012, Article ID 309196, 12 pages
Clinical Study

Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study

1Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC 27109, USA
2Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC 27157, USA
3Department of Internal Medicine, The University of Tennessee-Memphis, Memphis, TN 38103, USA
4Section on Clinical, Behavioral & Outcomes Research, Harvard Medical School, Boston, MA 22222, USA
5Department of Health and Physical Activity, University of Pittsburgh, Pittsburgh, PA 15203, USA
6Indian Health Service/ACKCO, Inc/NIDDK, Northern Navajo Medical Center, Shiprock, NM 87420, USA
7Diabetes Epidemiology and Clinical Research Section, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ 85014, USA
8Department of Cardiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA

Received 18 May 2012; Accepted 14 September 2012

Academic Editor: Jonathan N. Myers

Copyright © 2012 Paul M. Ribisl et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The primary aims of this paper were (1) to evaluate the influence of intensive lifestyle weight loss and exercise intervention (ILI) compared with diabetes support and education (DSE) upon Heart Rate Recovery (HRR) from graded exercise testing (GXT) and (2) to determine the independent and combined effects of weight loss and fitness changes upon HRR. In 4503 participants (45–76 years) who completed 1 year of intervention, HRR was measured after a submaximal GXT to compare the influence of (ILI) with (DSE) upon HRR. Participants assigned to ILI lost an average 8.6% of their initial weight versus 0.7% in DSE group ( ) while mean fitness increased in ILI by 20.9% versus 5.8% in DSE ( ). At Year 1, all exercise and HRR variables in ILI improved ( ) versus DSE: heart rate (HR) at rest was lower ( versus  b/min), HR range was greater ( versus  b/min), HR at 2 minutes was lower ( versus  b/min), and HRR was greater ( versus  b/min). Weight loss and fitness gain produced significant separate and independent improvements in HRR.