Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats
Table 2
Tibial structural properties.
Lean
Obese
Flexural rigidity (N·mm2·103)
5.37 ± 0.81
5.40 ± 0.34
5868
Load at proportional limit (N)
25.49 ± 2.94*
30.22 ± 3.41
Displacement at proportional limit (mm)
0.26 ± 0.04*
0.30 ± 0.02
Maximal load (N)
36.13 ± 4.48
39.34 ± 3.67
26
Displacement at maximal load (mm)
0.61 ± 0.10
0.60 ± 0.08
1272
Energy to proportional limit (N·mm·103)
4.12 ± 0.76
5.06 ± 0.89
49
Energy to maximal load (N·mm·104)
1.78 ± 0.45
1.56 ± 0.78
123
Values are means ± SD. *denotes statistically significant (). denotes the sample size per group needed for the recorded differences to become statistically significant based on a power of 0.8.