Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats

Table 5

𝐿₆ structural properties.

	Lean	Obese	𝑛
Stiffness (N·mm^−1)	244.01 ± 19.80	248.52 ± 34.23	564
Load at proportional limit (N)	120.84 ± 19.56	101.34 ± 20.34	17
Displacement at proportional limit (mm)	0.75 ± 0.15^*	0.56 ± 0.09
Maximal load (N)	137.88 ± 17.90	132.58 ± 20.16	203
Displacement at maximal load (mm)	1.07 ± 0.32	1.30 ± 0.46	46
Energy to proportional limit (N·mm·10^3)	8.69 ± 2.82	5.91 ± 1.95	12
Energy to maximal load (N·mm·10^4)	1.87 ± 0.71	2.64 ± 1.31	27

Values are means ± SD. ^*denotes statistically significant (𝑃≤0.05). 𝑛 denotes the sample size per group needed for the recorded differences to become statistically significant based on a power of 0.8.