Table 2: Odds ratios (ORs) of colon cancer for BMI by age, decadesa.

All postmenopausal womenPostmenopausal women with no HRTPostmenopausal women with HRT
Case/controlOR 𝑃 𝑃 Case/controlOR 𝑃 𝑃

Normalc (ref)147/3151.0072/1051.0075/2101.00
BMI 2 yrsbOverweight159/3020.98 (0.73–1.32)0.8887/1170.95 (0.60–1.49)0.8272/1851.01 (0.67–1.52)0.96
Obese188/2791.25 (0.92–1.69)0.160.19120/1231.39 (0.89–2.17)0.150.1168/1561.21 (0.78–1.87)0.390.57
Normal (ref)192/4101.00101/1451.0091/2651.00
BMI 50sOverweight125/2420.96 (0.74–1.32)0.7773/911.06 (0.68–1.65)0.7952/1510.95 (0.58–1.40)0.66
Obese126/1631.27 (0.97–1.92)0.070.1970/791.18 (0.72–1.93)0.500.6456/841.74 (1.08–2.80)0.020.08
Normal (ref)250/5291.00127/1921.00123/3371.00
BMI 40sOverweight101/1761.07 (0.78–1.47)0.6657/641.29 (0.80–2.07)0.3044/1121.01 (0.65–1.59)0.93
Obese71/1141.25 (0.85–1.82)0.260.4343/591.18 (0.69–2.00)0.540.8128/551.45 (0.82–2.57)0.200.25
Normal (ref)306/6291.00159/2271.00147/4021.00
BMI 30sOverweight66/1151.06 (0.74–1.52)0.7637/521.02 (0.60–1.72)0.9529/631.11 (0.65–1.87)0.71
Obese42/561.42 (0.90–2.27)0.130.9027/271.50 (0.80–2.83)0.210.4715/291.38 (0.68–2.83)0.380.76
Normal (ref)333/6501.00178/2501.00153/4001.00
BMI 20sOverweight48/741.15 (0.76–1.75)0.5029/301.32 (0.73–2.40)0.3519/441.10 (0.60–2.02)0.77
Obese18/360.87 (0.47–1.63)0.670.5013/200.85 (0.38–1.87)0.680.205/160.91 (0.31–2.65)0.860.93

aAdjusted for age, race, gender, education, income, physical activity, smoking, alcohol, nonsteroidal anti-inflammatory drugs use, family history of colorectal cancer, age at menarche, and parity. b2 years before recruitment/interview. cNormal: ≥18.5 to <25 kg/m2; overweight: ≥25 to <30 kg/m2; obese: ≥30 kg/m2. * 𝑃 value for trend.