Weight Status in Persons with Multiple Sclerosis: Implications for Mobility Outcomes
Table 2
Descriptive characteristics and effect sizes for mobility outcomes by BMI classification.
Outcome
Descriptive characteristics
Effect sizes
Normal weight
Overweight
Obese
Normal
Normal
Overweight
versus Overweight
versus Obese
versus Obese
Walking performance
T25FW, s
7.1 (4.3)
6.9 (5.1)
6.2 (2.2)
.05
.29
.18
6MW, m
396.4 (175.4)
438.4 (131.7)
422.2 (100.3)
−.27
−.19
.14
Walking cost
, mL/kg/m
0.256 (0.136)
0.221 (0.144)
0.202 (0.046)
.25
.62
.20
Spatiotemporal gait
Velocity, cm/s
97.1 (30.8)
105.6 (28.9)
107.1 (29.9)
−.28
−.33
−.05
Cadence, steps/min
100.6 (14.9)
103.6 (17.8)
105.5 (14.7)
−.19
−.33
−.12
Step length, cm
56.5 (13.2)
60.0 (11.5)
59.5 (12.0)
−.28
−.24
.04
Step time, s
0.624 (0.116)
0.618 (0.196)
0.588 (0.095)
.04
.34
.21
Double support, gait cycle (%)
32.5 (6.2)
31.6 (6.9)
32.8 (5.7)
.13
−.05
−.18
Single support, gait cycle (%)
34.2 (3.6)
34.3 (3.4)
33.7 (2.9)
−.03
.17
.21
Base of support, cm
12.3 (5.1)
11.7 (3.6)
12.4 (3.6)
.13
−.02
−.18
Self-reported walking
MSWS-12
45.8 (32.0)
40.5 (27.8)
42.3 (26.3)
.18
.12
−.07
Free-living activity
Daily step count
3951.0 (2404.1)
4701.1 (2913.8)
3953.6 (1926.6)
−.28
−.001
.31
Daily movement count
139562.7 (88691.9)
154247.3 (95943.1)
139566.3 (67516.0)
−.16
<.001
.18
Values are mean (SD). BMI: body mass index; T25FW: timed 25-foot walk; 6MW: 6-minute walk; : oxygen cost of walking; MSWS-12: Multiple Sclerosis Walking Scale-12.
