Systemic Inflammation and Lung Function Impairment in Morbidly Obese Subjects with the Metabolic Syndrome

Table 3

Pulmonary function test of subjects with and without metabolic syndrome.

	No metabolic syndrome (𝑛=159)	Metabolic syndrome (𝑛=293)	𝑃 value
FEV1 (% predicted)	93.0 ± 13.9	91.2 ± 14.5	0.206^3
FVC (% predicted)	100.6 ± 14.0	98.5 ± 14.7	0.206
FEV1/FVC	78.2 ± 6.9	76.7 ± 6.4	0.032
FEF25–75 (% predicted)	77.4 ± 24.0	73.9 ± 23.3	0.152
Reversibility FEV1 > 12%	6%	7%	0.523^2
FeNO (ppb)^1	19.3 ± 22.4	17.6 ± 12.6	0.541

¹Data were log transformed before comparison.
²Data presented as percentage, 𝑃 value for Chi-square analysis.
³Data presented as mean ± standard deviation, 𝑃 values for Student 𝑡-test.
FEV₁: forced expired volume in 1 second; FVC: forced vital capacity; FEF_25–75: forced expiratory flow 25%–75%; TLC: total lung capacity; FeNO: fractional expiratory nitric oxide.