Retrospective Reports of Weight Change and Inflammation in the US National Health and Nutrition Examination Survey
Table 3
Odds ratios from logistic regression models predicting high levels of C-reactive protein and White blood cell count by 1- and 10-year change in weight categorizes.
High C-reactive protein*
High White blood cell count*
Model I
Model II
Model I
Model II
OR
(95% CI)
OR
(95% CI)
OR
(95% CI)
OR
(95% CI)
Weight change in past 1 year
Loss
≥10 kg
1.67
(1.08–2.60)
1.61
(1.03–2.50)
1.25
(0.81–1.93)
1.13
(0.73–1.75)
4–9 kg
0.98
(0.70–1.37)
0.92
(0.70–1.38)
1.21
(0.89–1.64)
1.22
(0.89–1.67)
Stable (<4 kg)
Reference
Reference
Reference
Reference
Gain
4–9 kg
1.28
(0.70–1.37)
1.30
(0.92–1.83)
1.22
(0.89–1.68)
1.27
(0.91–1.77)
≥10 kg
1.94
(1.10–3.43)
1.96
(1.10–3.50)
0.97
(0.54–1.74)
0.97
(0.55–1.73)
Weight change in past 10 years
Loss
≥10 kg
1.24
(0.78–1.99)
1.24
(0.77–2.00)
1.21
(0.78–1.86)
1.19
(0.77–1.84)
4–9 kg
1.26
(0.83–1.90)
1.23
(0.82–1.86)
1.29
(0.88–1.90)
1.21
(0.82–1.78)
Stable (<4 kg)
Reference
Reference
Reference
Reference
Gain
4–9 kg
1.24
(0.91–1.69)
1.27
(0.93–1.73)
1.01
(0.75–1.36)
1.06
(0.78–1.42)
≥10 kg
1.62
(1.16–2.27)
1.62
(1.16–2.26)
0.96
(0.69–1.33)
0.92
(0.66–1.29)
*High levels included individuals in the highest sample-based quartile (CRP > 0.51 mg/dL; WBC > cells/L). Model I adjusts for age, sex, and current BMI. Model II adjusts for current smoking status and total cholesterol in addition to Model I covariates. OR: odds ratio; CI: confidence interval. Bold indicates significant at the .05 level.
