The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals

Table 2

Baseline correlations (Pearson’s regression) of several parameters with ox-LDL, MPO, and Lp-PLA₂ activity in subjects with and without the metabolic syndrome (𝑛=100).

Variable	ox-LDL (U/L)		MPO^a (pM)		Lp-PLA2 activity (nmol/mL/min)
	𝑅	𝑃	𝑅	𝑃	𝑅	𝑃
Weight (kg)	0.195	0.056	0.275	0.007	0.203	0.047
Waist (in)	0.202	0.052	0.253	0.015	0.234	0.024
BMI (kg/m^2)	0.128	0.212	0.300	0.003	0.062	0.544
SBP (mmHg)	0.092	0.372	0.078	0.445	0.015	0.883
DBP (mmHg)	0.196	0.055	0.023	0.822	0.066	0.523
Glucose^a (mg/dL)	−0.033	0.749	0.095	0.357	0.106	0.303
Insulin^a (mU/L)	0.153	0.134	0.296	0.003	0.064	0.536
HOMA-IR^a	0.129	0.207	0.283	0.005	0.079	0.445
Triglycerides^a (mg/dL)	0.479	0.000	−0.018	0.858	0.292	0.004
HDL (mg/dL)	−0.231	0.023	−0.108	0.292	−0.404	0.000
LDL (mg/dL)	0.629	0.000	−0.001	0.993	0.309	0.003
Total cholesterol (mg/dL)	0.687	0.000	−0.052	0.612	0.297	0.003
ox-LDL (U/L)	—	—	0.004	0.968	0.378	0.000
MPO^a (pM)	0.004	0.968	—	—	0.117	0.254
Lp-PLA2 Activity (nmol/mL/min)	0.378	0.000	0.117	0.254	—	—

aVariables are not normally distributed. Log-transformed value before regression.