Clinical Study

Lifestyle Intervention Involving Calorie Restriction with or without Aerobic Exercise Training Improves Liver Fat in Adults with Visceral Adiposity

Table 1

Changes in diet-induced weight loss with or without aerobic exercise on anthropometric parameter, dietary intake, cardiorespiratory fitness, and step counts.

CR ( )CR + Ex ( ) value
BeforeAfterBeforeAfter valu group × time
Av ± SEMAv ± SEMAv ± SEMAv ± SEMinteraction

Age (yrs)52 ± 2 61 ± 2 <0.001
Anthropometric parameter
 Height (cm)158.2 ± 7.3 158.4 ± 7.5 158.3 ± 6.3 158.3 ± 6.20.9580.354
 Weight (kg)71.3 ± 3.2 65.9 ± 2.7***68.6 ± 3.0 63.6 ± 2.8***0.5570.786
 Body mass index (kg/m2)28.4 ± 1.0 26.2 ± 0.9***27.3 ± 1.1 25.3 ± 1.0***0.4810.740
 Percent body fat (%)35.6 ± 1.8 31.3 ± 1.8***35.5 ± 1.5 31.6 ± 1.5***0.9750.707
 Body fat mass (kg)25.9 ± 2.0 21.0 ± 1.6***24.6 ± 1.6 20.2 ± 1.4***0.6170.635
 Lean body mass (kg)46.1 ± 2.0 45.6 ± 2.0 44.4 ± 2.2 43.4 ± 2.0*0.5560.537
 Visceral fat area (cm2)164 ± 10 139 ± 10***165 ± 10 127 ± 10***0.9530.075
 Subcutaneous fat area (cm2)321 ± 28 282 ± 25***287 ± 21 250 ± 22***0.3640.900
 Liver-to-spleen ratio (HU/HU)1.11 ± 0.09 1.23 ± 0.05*1.15 ± 0.05 1.28 ± 0.03**0.6810.984
Dietary intake
 Energy intake (kcal/day)1820 ± 89 1429 ± 76***2051 ± 83 1704 ± 75***0.0680.658
 Protein (g/day)70.8 ± 4.8 57.9 ± 2.4**82.7 ± 3.9 71.3 ± 4.6**0.0690.759
 Fat (g/day)51.4 ± 3.1 39.3 ± 3.3**64.0 ± 3.7 48.6 ± 2.9**0.0140.550
 Carbohydrate (g/day)260.5 ± 11.8 207.6 ± 12.2***279.3 ± 12.4 241.8 ± 10.3**0.2790.273
Cardiorespiratory fitness and step counts
 VO2peak/kg (mL/min/kg weight)††23.0 ± 1.0 24.1 ± 2.2 20.7 ± 1.2 23.8 ± 1.3*0.1390.444
 Watts at lactate threshold (watts) †††53 ± 4 53 ± 4 49 ± 4 58 ± 3*0.4320.053
 Step counts (counts/day)††††6458 ± 654 7578 ± 763 7124 ± 849 9412 ± 905**0.5360.257

CR: calorie restriction-induced weight loss; CR + Ex: calorie restriction-induced weight loss with aerobic exercise.
Before versus after; * , ** , and *** .
value for baseline characteristics (CR group versus CR + Ex group).
CR ( ); ††CR + Ex ( ); †††CR ( ); ††††CR ( ); CR + Ex ( ).