Early Life Exposure to Fructose and Offspring Phenotype: Implications for Long Term Metabolic Homeostasis

Figure 1

Fetal weight (a) and placental weight (b) at fetal day 21 (E21) and maternal plasma fructose levels at E21 and P10 (c) and maternal plasma insulin levels in Cont and Fr dams at E21 (d). Maternal fructose intake had no effect on fetal weight but significantly decreased placental weight in female fetuses, 𝑃<0.05. Sample size: Cont male(𝑛=10), Fr male(𝑛=9), Cont female(𝑛=10), and Fr female(𝑛=9). Maternal fructose intake significantly increased maternal fructose at E21 and P10 and insulin levels at P10. Data are means ± SEM; 𝑛=9-10 per group (E21) and 𝑛=5–8 per group (P10). *𝑃<0.05. Cont = control; Fr = fructose. Data from Vickers et al. (2011).

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