Complement Receptors C5aR and C5L2 Are Associated with Metabolic Profile, Sex Hormones, and Liver Enzymes in Obese Women Pre- and Postbariatric Surgery
Figure 1
Association of liver C5L2 mRNA expression with circulating estrogen levels. mRNA was extracted from liver biopsies and reverse-transcribed to cDNA and gene expression was evaluated by RT-PCR with the indicated primers with all results expressed relative to GAPDH using the method as described in detail in Section 2. (a) Hepatic mRNA expression levels of C3 and the three related receptors (C5L2, C3aR, and C5aR) in the pre- versus postmenopausal groups. ((b) and (c)) Linear correlation plot of C5L2 mRNA expression with plasma estradiol (E2) and estrone (E1).
