Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation

Figure 6

Levels of insulin and the proinflammatory cytokines IL-6 and TNFα in plasma. Insulin levels (ng/mL) were measured with ELISA in plasma obtained from the mice at termination, for (a) females and (b) males (median and individual values are shown as columns and dots, resp.). IL-6 (c) and TNFα (d) levels (both in pg/mL) were measured with bead-based immunoassays and analysed by flow cytometer in plasma obtained from the mice at termination. The data shown are from females and males combined (median and individual values are shown as columns and dots, resp.). mice (3 of each gender).

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