The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min/+ Mice as Adults

Figure 8

Mean fasted blood glucose levels at age 10 weeks as area under the curve (AUC) (arbitrary units) in the glucose tolerance test in (a) female and (b) male Min/+ mice, and in (c) female and (d) male wild-type mice. The symbols for the untreated mice of both genders are: 10+10+10 (●), 45+10+10 (△), 10+45+10 (▽), 45+45+10 (□), 10+10+45 (◊), and 45+45+45 (open hexagon), and the symbols for the PhIP-treated mice are in grey color; 45+45+10 PhIP (○) and 45+45+45 PhIP (△). The experimental groups are as explained in the legend to Figure 1. .

(a)

(b)

(c)

(d)