|
| | Eid et al.
SOARD 2005
[16] | Stroh et al.
Zentralbl
Chir 2008
(paper in
German,
abstract in
English)
[13] | Doblado
et al. Ferti
Steril 2010
[19] | Jamal et al.
SOARD
2012 [17] | Talebpour
Obes Surg 2011
(abstract
only) [18] | George and Azeez
Obes Surg
2013
(abstract
only) [20] |
|
| Participants | 24 women with
PCOS | 3 females
with PCOS | 2 females with
infertility
secondary to
PCOS (and to
male factor) | 10 women
with PCOS
and infertility | 69 premenopausal
married
females | 156 women
(67 had
radiological
features of
PCOS and 11
were infertile) |
| Interventions | Laparoscopic
RYGB | Laparoscopic
LAGB | RYGB and
gastric band,
respectively | RYGB | Gastric
plication or
RYGB | Laparoscopic
SG |
Outcomes
measured | Mean excess
weight loss,
presence of
hirsutism,
regular
menstruation,
conception rate
after surgery,
obesity
associated comorbidities | % EWL,
glucose
levels,
conception
rate | Conception
and pregnancy | Pre- and postsurgery
conception
rate,
weight loss,
hirsutism,
menstrual
dysfunction,
obesity
associated comorbidities | Regularity of
menstruation
and
conception
rate | Hirsutism,
stress urinary
incontinence,
menstrual
dysfunction,
infertility |
| Study design | Retrospective | Not stated | Retrospective | Retrospective | Not stated | Retrospective |
| Mean follow-up (months) | | 104 | Not stated | | 12 | Not stated |
| Results, fertility | 5 women
(previously
infertile) who
wanted to
conceive were
able to do so
after surgery
without the use
of clomiphene | One patient
(33%)
conceived
postoperatively | Following
IVF/ICSI, both
women
became
pregnant and
had
uncomplicated
deliveries | 100% postoperative
conception
rate in
infertile
patients with
PCOS who
desired
pregnancy | 10 women
(71%) out of
14 who were
infertile preoperatively became
pregnant
after one
year postoperatively | 4 patients
(36%)
conceived
without any
formal fertility
treatment |
Results –
other | Resolution of
T2D, decreased
number of
patients with
hypertension
and
hyperlipidemia,
improvement
of PCOS-associated
symptoms | The 3
patients had a
% EWL of
49, 67, and
41%,
respectively,
with glucose
levels
normalized
postoperatively | | Improvement
of glycemic
control,
PCOS-associated
symptoms,
hypertension,
depression,
GERD, and
urinary
incontinence | Out of 30
patients with
irregular
cycles preoperatively, 14 (47%)
had regular
cycles by the
end of 1 year
postoperatively | Hirsutism and
radiological
evidence of
PCOS resolved
in 80%;
menstrual
dysfunction
improved in
100%; urinary
incontinence
resolved or
improved in
42% |
|
