Table 2: Relative organ weight for mice treated with UP601 in HFD-induced mouse obesity model.

GroupsLiverFat deposition
EpididymalRetroperitonealPerirenal Mesenteric Total

NC3.49 ± 0.61 2.38 ± 1.030.62 ± 0.330.33 ± 0.101.04 ± 0.294.37 ± 1.70
HFD3.54 ± 0.814.94 ± 0.761.14 ± 0.161.31 ± 0.153.51 ± 0.4810.90 ± 0.63
Orlistat (40 mg/kg)2.61 ± 0.455.78 ± 0.871.36 ± 0.250.98 ± 0.212.54 ± 0.5210.66 ± 1.07
UP601 (1.3 g/kg)3.14 ± 0.134.36 ± 0.531.44 ± 0.150.63 ± 0.091.43 ± 0.327.55 ± 0.82

≤ 0.05; ≤ 0.001; ≤ 0.0001. values versus HFD group.