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Journal of Obesity
Volume 2016, Article ID 6170719, 7 pages
http://dx.doi.org/10.1155/2016/6170719
Review Article

A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery

1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada T6G 2R7
2Department of Surgery, University of Alberta, Edmonton, AB, Canada T6G 2B7
3Center for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandra Hospital, Edmonton, AB, Canada T5H 3V9
4Department of Surgery, University of Calgary, Calgary, AB, Canada T2N 2T9

Received 2 February 2016; Accepted 10 May 2016

Academic Editor: Francesco Saverio Papadia

Copyright © 2016 Alexandra Chow et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The utility of bariatric surgery in type 1 diabetes remains controversial. The aim of the present study is to evaluate glycemic control outcomes in obese patients with type 1 diabetes after bariatric surgery. Methods. A comprehensive search of electronic databases was completed. Inclusion criteria included human adult subjects with BMI ≥35 kg/m2 and a confirmed diagnosis of type 1 diabetes who underwent a bariatric surgical procedure. Results. Thirteen primary studies (86 patients) were included. Subjects had a mean age of years with a mean BMI of  kg/m2. There was a marked reduction in BMI postoperatively at 12 months and at study endpoint to  kg/m2 () and  kg/m2 (), respectively. Preoperative weighted mean total daily insulin requirement was  IU/d, which decreased significantly to  IU/d () and  IU/d () at 12 months and at study endpoint, respectively. An improvement in HbA1c was also seen from % preoperatively to % () and % () at 12 months and at study endpoint, respectively. Conclusion. Bariatric surgery in patients with type 1 diabetes leads to significant reductions in BMI and improvements in glycemic control.