Review Article

Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature

Figure 2

Proposed mechanism of the changes in gut hormonal axis by gut microbiota. TG: triglycerides, LPL: lipoprotein lipase, Fiaf: fasting induced adipocyte factor, ANGPTL-4: angiopoitein-like protein-4, GLP-1: glucagon like peptide-1, GPR43 and GPR41: G protein coupled receptors 43 and 41, PYY: peptide YY, and SCFA: short chain fatty acids. Minus sign indicates inhibitory effect; plus sign indicates stimulatory effect.