Clinical Study

Do Lactation-Induced Changes in Ghrelin, Glucagon-Like Peptide-1, and Peptide YY Influence Appetite and Body Weight Regulation during the First Postpartum Year?

Table 4

Anthropometric characteristics and fasting hormone concentrations of postpartum lactating and never-pregnant control women completing the longitudinal study.

CharacteristicNever-pregnant women ()Lactating women ()
Baseline6 months12 monthsBaseline6 months12 months

Height (cm)169.5 5.5169.0 5.9169.0 5.9168.1 7.7168.1 7.8168.1 7.9NS
Weight (kg)68.6 8.669.1 9.068.7 9.970.8 9.266.5 10.165.6 9.5
BMI (kg/m2)24.2 2.724.2 2.924.1 3.225.0 3.423.6 3.823.0 3.8
Body fat (%)35.3 5.736.0 5.935.8 6.238.9 5.835.9 7.134.5 7.9
Fat mass (kg)23.6 6.424.2 6.823.9 7.626.5 6.923.5 8.022.2 8.2
Lean mass (kg)42.4 3.342.1 3.242.1 3.640.7 3.940.2 3.640.3 4.2
Body fat gynoid (%)45.2 4.545.2 4.545.3 5.048.2 4.645.5 6.344.0 6.6
Body fat android (%)37.8 9.039.5 9.038.2 9.342.7 8.039.3 8.837.3 10.4
Waist circumference (cm)81.7 8.381.3 8.479.0 16.292.9 7.682.4 16.182.0 9.1
Hip circumference (cm)99.6 7.4102.3 5.398.4 17.8102.9 8.297.2 17.599.4 8.4NS

Prolactin (ng/mL)18.0 5.823.2 4.326.6 4.658.2 5.630.0 4.221.5 4.4
Leptin (ng/mL)15.1 10.015.6 9.116.3 8.714.1 7.413.8 8.713.2 9.9
Insulin (U/mL)0.7 1.90.9 2.21.9 3.60.2 0.71.1 1.31.9 4.0
Ghrelin (pg/mL)830.6 358.81111.7 812.0693.9 318.2731.9 242.4750.2 358.8704.2 301.8
Ghrelin (pg/mL)105.9 83.4133.7 85.683.9 67.8101.6 107.879.0 56.579.2 79.8
PYY (pg/mL)110.7 41.4126.6 44.2138.4 38.2101.0 31.1137.7 43.7140.9 49.8
GLP-1 (pM)14.8 9.215.3 9.016.1 6.612.0 5.912.4 6.311.4 4.0

Ghrelin, acylated (active) ghrelin; group by time interaction, ; time effect, .