Journal of Obesity / 2017 / Article / Tab 5 / Research Article
Web-Based Interventions Alone or Supplemented with Peer-Led Support or Professional Email Counseling for Weight Loss and Weight Maintenance in Women from Rural Communities: Results of a Clinical Trial Table 5 Linear mixed
tests of pairwise group comparisons of estimated difference in change by phase of intervention.
Outcome Phase 1 Phase 2 Phase 3 Baseline to 6 months 6 months to 18 months 18 months to 30 months Pairwise comparison Estimated mean difference (95% CI) Estimated mean difference (95% CI) Estimated mean difference (95% CI) Body weight WO versus WD 0.138 0.9 (−0.8 to 2.7) 0.360 0.2 (−1.1 to 1.6) 0.268 −0.4 (−1.8 to 0.9) WO versus WE 0.188 −0.8 (−2.5 to 0.9) 0.411 −0.2 (−1.5 to 1.2) 0.444 −0.1 (−1.4 to 1.2) WD versus WE 0.047 −1.7 (−3.4 to 0.0) 0.563 −0.4 (−1.7 to 1.0) 0.632 0.3 (−1.0 to 1.7) Waist circumference WO versus WD 0.070 1.6 (−0.5 to 3.7) 0.497 −0.01 (−1.5 to 1.4) 0.479 −0.04 (−1.5 to 1.4) WO versus WE 0.461 0.1 (−2.0 to 2.2) 0.441 −0.1 (−1.5 to 1.3) 0.463 −0.1 (1.5 to 1.3) WD versus WE 0.164 −1.5 (−3.5 to 0.6) 0.891 −0.1 (−1.6 to 1.4) 0.970 −0.03 (−1.5 to 1.4) Kcal intake daily WO versus WD 0.105 −96.9 (−248.7 to 55.0) 0.473 −4.7 (−138.8 to 129.3) 0.134 −67.3 (−186.5 to 52.0) WO versus WE 0.139 −83.5 (−234.6 to 67.7) 0.289 −37.6 (−170.5 to 95.2) 0.183 53.6 (−62.8 to 170.0) WD versus WE 0.861 13.4 (−137.2 to 164.1) 0.633 −32.9 (−168.4 to 102.6) 0.050 120.9 (0.0 to 241.8) Weekly minutes ≥ moderate intensity activity (Actigraph) WO versus WD 0.497 −0.2 (−38.3 to 37.9) 0.271 10.9 (−24.2 to 46.0) 0.373 −6.0 (−42.2 to 30.2) WO versus WE 0.332 −8.3 (−46.0 to 29.3) 0.270 10.9 (−24.1 to 45.9) 0.240 12.9 (−23.0 to 48.7) WD versus WE 0.672 −8.2 (−46.1 to 29.8) 0.999 0.02 (−35.6 to 35.7) 0.313 18.9 (−17.9 to 55.6) Weekly minutes ≥ moderate intensity activity WO versus WD 0.207 −30.6 (−104.2 to 43.0) 0.055 51.6 (−11.7 to 114.8) 0.344 −10.1 (−59.8 to 39.6) WO versus WE 0.427 6.8 (−66.4 to 80.0) 0.336 13.5 (−49.1 to 76.1) 0.288 −13.8 (−62.5 to 34.8) WD versus WE 0.314 37.4 (−35.6 to 110.5) 0.238 −38.1 (−101.4 to 25.2) 0.885 −3.7 (−54.2 to 46.7) Systolic blood pressure WO versus WD 0.209 1.3 (−1.9 to 4.6) 0.318 −0.9 (−4.8 to 2.9) 0.419 0.4 (−3.3 to 4.0) WO versus WE 0.137 −1.8 (−5.1 to 1.4) 0.395 −0.5 (−4.3 to 3.3) 0.310 0.9 (−2.7 to 4.5) WD versus WE 0.054 −3.2 (−6.4 to 0.1) 0.833 0.4 (−3.4 to 4.3) 0.782 0.5 (−3.2 to 4.2) Diastolic blood pressure WO versus WD 0.317 0.5 (−1.4 to 2.3) 0.431 −0.2 (−2.4 to 2.0) 0.468 −0.1 (−2.2 to 2.1) WO versus WE 0.216 −0.7 (−2.6 to 1.1) 0.215 −0.9 (−3.1 to 1.3) 0.342 0.4 (−1.7 to 2.5) WD versus WE 0.205 1.2 (−3.0 to 0.7) 0.548 −0.7 (−2.9 to 1.6) 0.639 0.5 (−1.7 to 2.7) Total cholesterol (mL/dL) WO versus WD 0.473 0.4 (−10.2 to 11.0) 0.094 7.2 (−3.5 to 17.9) 0.154 −4.3 (−12.7 to 4.0) WO versus WE 0.026 −10.4 (−20.8 to 0.1) 0.076 7.7 (−2.8 to 18.3) 0.116 −5.0 (−13.2 to 3.2) WD versus WE 0.043 −10.8 (−21.2 to −0.3) 0.918 0.6 (−10.2 to 11.3) 0.873 −0.7 (−9.2 to 7.8) HDL (mL/dL) WO versus WD 0.060 −2.2 (−5.0 to 0.6) 0.365 0.4 (−2.1 to 3.0) 0.147 1.4 (−1.2 to 4.1) WO versus WE −4.0 (−6.8 to −1.3) 0.062 2.0 (−0.5 to 4.4) 0.273 −0.8 (−3.4 to 1.8) WD versus WE 0.196 −1.8 (−4.6 to 0.9) 0.241 1.5 (−1.0 to 4.0) 0.105 −2.2 (−4.9 to 0.5) LDL (mL/dL) WO versus WD 0.350 1.6 (−6.7 to 10.0) 0.081 6.1 (−2.5 to 14.8) 0.064 −5.6 (−12.7 to 1.6) WO versus WE 0.079 −5.9 (−14.1 to 2.3) 0.023 8.7 (0.2 to 17.2) 0.029 −6.8 (−13.8 to 0.2) WD versus WE 0.072 −7.5 (−15.8 to 0.7) 0.561 2.6 (−6.1 to 11.3) 0.732 −1.3 (−8.5 to 6.0) Triglycerides (mL/dL) WO versus WD 0.370 3.1 (−15.0 to 21.1) 0.429 −1.4 (−16.6 to 13.8) 0.337 3.2 (−11.9 to 18.4) WO versus WE 0.477 0.5 (−17.4 to 18.4) 0.028 −14.7 (−29.8 to 0.3) 0.023 15.3 (0.4 to 30.3) WD versus WE 0.782 −2.5 (−20.4 to 15.4) 0.089 −13.3 (−28.7 to 2.0) 0.123 12.1 (−3.3 to 27.5) Fasting glucose (mL/dL) WO versus WD 0.081 2.7 (−1.1 to 6.5) 0.141 −2.0 (−5.7 to 1.7) 0.360 0.6 (−2.9 to 4.2) WO versus WE 0.024 3.8 (0.1 to 7.6) 0.195 −1.6 (−5.2 to 2.0) 0.046 −3.0 (−6.4 to 0.5) WD versus WE 0.565 1.1 (−2.7 to 4.9) 0.827 0.4 (−3.3 to 4.1) 0.047 −3.6 (−7.2 to 0.0)
maximum likelihood methods were used to analyze a mixed-effects repeated-measures model (random intercept, unstructured variance/covariance matrix), with tests of pairwise contrasts of group differences in the change in outcome from beginning to end of each phase. of web-based with discussion board (WD) and web-based with email counseling (WE) with web-based only (WO) were one-tailed and WD with WE were two-tailed, each tested at . also included data collected at 3, 12, and 24 months, but comparisons focused on group differences in change from the beginning to the end of each phase. effect was not in hypothesized direction.