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Journal of Obesity
Volume 2017, Article ID 1935204, 5 pages
Research Article

Outcomes of Bariatric Surgery in Morbidly Obese Patients with Multiple Sclerosis

1Bariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH, USA
2Department of General Surgery, Cleveland Clinic, Cleveland, OH, USA
3Department of Neurology, Cleveland Clinic, Cleveland, OH, USA
4Mellen Center for Multiple Sclerosis, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA

Correspondence should be addressed to Kalman Bencsath; gro.fcc@kascneb

Received 24 August 2016; Revised 13 January 2017; Accepted 1 February 2017; Published 19 February 2017

Academic Editor: Eliot Brinton

Copyright © 2017 Kalman Bencsath et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Obesity is common in patients with multiple sclerosis (MS); however, safety and efficacy of bariatric surgery in this population remain unclear. A database of 2,918 was retrospectively reviewed, yielding 22 (0.75%) severely obese patients with MS who underwent bariatric surgery. Sixteen surgical patients with complete follow-up data were matched to a nonsurgical control group of MS patients, based on age, BMI, MS subtype, and length of follow-up. MS relapse rates and trends in the timed twenty-five foot walk test (T25FW) were compared. In the surgical group (gastric bypass , sleeve gastrectomy ), preoperative BMI was 46.5 ± 7.2 Kg/m2 and average excess weight was 60.4 kg. Follow-up data was collected at 59.0 ± 29.8 months. There were two major and four minor complications. Five patients required readmission and there were no mortalities. Percent excess weight loss was 75.5 ± 27.0%. In the 16 patients with follow-up data, patients who underwent bariatric surgery were significantly faster on the T25FW compared to the nonsurgical population. In conclusion, bariatric surgery is relatively safe and effective in achieving weight loss in patients with MS. In addition, surgery may help patients maintain ambulation. Findings support the need for further studies on bariatric surgery and disease-specific outcomes in this population.