FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population

Figure 4

Effect of the FTO rs9939609 genotype on energy intake, TSS, and R2D : 4D stratified by category of PA. values are for the interaction between the FTO variant and PA category; least-squares means of different genotypes across all PA groups were calculated by using Robust Linear Regression analysis, with adjustment for age and sex. Allele frequency by PA category was low: 20/43/14; moderate: 28/34/13; high: 27/13/9 for TT, TA, and AA genotypes, respectively. TSS: time spent sitting. R2D : 4D; ratio of the left hand second digit to the fourth, and TSS; time spent sitting. Mean of each variable with genotype for high PA is different from mean of each genotype for low PA at but not in R2D : 4D TT and AA genotype.