Associations of Diabetes and Obesity with Risk of Abdominal Aortic Aneurysm in Men

Table 3

Hazard ratio of clinically diagnosed AAA in association with baseline history of diabetes overall and in subgroups.

Diabetes (yes versus no)		Basic	, interaction	Multivariable	, interaction
All men	471	1.08 (0.78–1.50)		0.79 (0.57–1.11)
Age			0.59		0.41
<65 years	97	0.75 (0.27–2.05)		0.45 (0.16–1.26)
≥65 years	374	1.10 (0.78–1.56)		0.86 (0.61–1.22)
Smoking status			0.59		0.51
Never	120	0.82 (0.38–1.77)		0.65 (0.30–1.42)
Ever	350	1.08 (0.75–1.55)		0.84 (0.58–1.21)
Alcohol use			0.73		0.74
Less than daily	262	1.17 (0.78–1.75)		0.86 (0.57–1.30)
More than daily	202	0.98 (0.55–1.76)		0.72 (0.40–1.30)
Vigorous exercise			0.36		0.33
Less than once per week	218	1.19 (0.78–1.81)		0.91 (0.60–1.40)
More than once per week	250	0.85 (0.49–1.46)		0.62 (0.36–1.08)
Hypertension			0.77		0.90
No	173	1.22 (0.64–2.32)		0.80 (0.42–1.54)
Yes	297	0.94 (0.64–1.37)		0.81 (0.55–1.18)
Hypercholesterolemia			0.99		0.98
No	223	1.05 (0.63–1.76)		0.81 (0.48–1.36)
Yes	242	1.06 (0.70–1.62)		0.80 (0.52–1.24)
Cardiovascular disease			0.41		0.58
No	362	1.09 (0.73–1.62)		0.83 (0.55–1.25)
Yes	109	0.80 (0.46–1.41)		0.74 (0.42–1.32)

adjusted for age, race, randomized treatment assignment (aspirin, β-carotene, vitamin E, vitamin C, multivitamin).
additionally adjusted for body mass index (continuous), smoking status (never, past, current), alcohol use (none, monthly, weekly, daily), vigorous exercise (<1 time/week, 1-2 times/week, 3-4 times/week, 5–7 times/week), and history of hypertension, hypercholesterolemia, cardiovascular disease (each yes, no), unless in the specific subgroup.