Research Article
Interleukin-1 Receptor Antagonist and Interleukin-4 Genes Variable Number Tandem Repeats Are Associated with Adiposity in Malaysian Subjects
Table 3
Logistic regression analysis for the association of IL1RA and IL4 VNTR with overall adiposity status.
| | Genotype/allele | Unadjusted | Adjusted | | Odds ratio (95% CI) | | Odds ratio (95% CI) | |
| | IL1RA (n; %) | | | | | | I/I (301; 95.6) | 1.00 | | 1.00 | | | I/II (13; 4.1) | 14.45 (3.14, 66.56) | 0.001 | 12.21 (2.54, 58.79) | 0.002 | | II/II (1; 0.3) | NP | 1.00 | NP | 1.00 | | I (615; 97.6) | 1.00 | | 1.00 | | | II (15; 2.4) | 6.81 (2.14, 21.66) | 0.001 | 5.78 (1.73, 19.29) | 0.004 | | IL4 (n; %) | | | | | | B1/B1 (192; 61.0) | 1.00 | | 1.00 | | | B1/B2 (88; 27.9) | 2.07 (0.99, 4.36) | 0.05 | 1.32 (0.57, 3.06) | 0.53 | | B2/B2 (35; 11.1) | 1.29 (0.74, 2.24) | 0.37 | 1.01 (0.55, 1.85) | 0.97 | | B1 (472; 74.9) | 1.00 | | 1.00 | | | B2 (158; 25.1) | 1.53 (1.04, 2.23) | 0.03 | 1.13 (0.74, 1.74) | 0.57 |
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Adjusted for covariate ethnicity; values are by logistic regression enter method; value significant at <0.05.
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