Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery

Figure 1

(a) The plot shows −log( values) for the top phenotypic associations between ICD-9-based diagnoses on the y-axis for VAT and SAT after controlling for age and sex. Point size indicates the number of cases (approximately 400, 800, 1200, and 1600). The direction of the point, upwards or downwards, represents the direction of the corresponding beta estimate (positive or negative) (b) Odds ratios and 95% confidence intervals (CIs) of top phenotypic associations of ICD-9 codes with VAT and SAT after controlling for age and sex. In both panels, SAT is represented in orange and VAT in blue. The red line corresponds to the Bonferroni threshold, whereas the green line corresponds to the 1% FDR threshold. Refer to the full descriptions of the ICD-9 code abbreviations in Supplementary Table 2.

(a)

(b)