Body Mass Index at Pediatric Leukemia Diagnosis and the Risks of Relapse and Mortality: Findings from a Single Institution and Meta-analysis

Table 2

Hazard ratios for the association between obesity status and relapse-free survival.

	Imputed				Complete set
Variables	HR	Lower 95% CI	Upper 95% CI	-value	HR	Lower 95% CI	Upper 95% CI	-value
Unadjusted
All
Overweight/obese vs non-overweight	1.77	0.91	3.46	0.09	1.75	0.85	3.40	0.13
<10 years
Overweight/obese vs non-overweight	0.52	0.08	3.39	0.48	0.33	0.04	2.56	0.29
≥10 years
Overweight/obese vs non-overweight	2.39	0.79	7.26	0.12	2.17	0.78	6.01	0.14
Sex and/or age adjusted
All
Overweight/obese vs non-overweight	1.57	0.71	3.45	0.26	1.45	0.67	3.14	0.34
Female vs male	0.56	0.29	1.08	0.08	0.46	0.22	0.99	0.046
Age at diagnosis	1.07	1.02	1.13	0.012	1.11	1.04	1.18	0.002
<10 years
Overweight/obese vs non-overweight	0.52	0.08	3.54	0.49	0.31	0.04	2.46	0.27
Female vs male	1.01	0.42	2.43	0.99	1.23	0.44	3.46	0.70
≥10 years
Overweight/obese vs non-.overweight	2.89	0.89	9.36	0.08	2.46	0.96	7.27	0.06
Female vs male	0.31	0.11	0.90	0.031	0.19	0.05	0.67	0.009

Hazard ratio.