Body Mass Index at Pediatric Leukemia Diagnosis and the Risks of Relapse and Mortality: Findings from a Single Institution and Meta-analysis

Table 3

Hazard ratios for the association between obesity status and overall survival.

	Imputed				Complete set
Variables	HR	Lower 95% CI	Upper 95% CI	-value	HR	Lower 95% CI	Upper 95% CI	-value
Unadjusted
All
Overweight/obese vs non-overweight	2.54	1.15	5.60	0.021	2.72	1.26	5.91	0.011
<10 years
Overweight/obese vs non-overweight	0.93	0.10	8.57	0.94	1.07	0.12	9.59	0.95
≥10 years
Overweight/obese vs non-overweight	1.74	0.67	4.56	0.25	1.75	0.70	4.36	0.23
Sex and/or age adjusted
All
Overweight/obese vs non-overweight	1.60	0.62	4.12	0.32	1.72	0.75	3.93	0.20
Female vs male	0.48	0.22	1.08	0.08	0.40	0.16	0.95	0.039
Age at diagnosis	1.18	1.09	1.27	<0.001	1.20	1.10	1.30	<0.001
<10 years
Overweight/obese vs non-overweight	0.89	0.09	8.62	0.92	1.05	0.17	9.39	0.97
Female vs male	1.63	0.36	7.32	0.53	1.61	0.27	9.65	0.60
≥10 years
Overweight/obese vs non-overweight	2.13	0.77	5.88	0.14	2.22	0.89	5.51	0.09
Female vs male	0.29	0.10	0.80	0.017	0.22	0.07	0.66	0.007

Hazard ratio.