Adiposity Is a Key Correlate of Circulating Fibroblast Growth Factor-21 Levels in African Males with or without Type 2 Diabetes Mellitus

Table 1

Anthropometric and biochemical characteristics of the study population.

Variable	Disease status
	Nondiabetic	T2DM
Number of subjects enrolled	106	101	-value
Weight, mean (SD), kg	77.7 (10)	80.6 (11.3)	0.045
Age, mean (SD), yrs	55.0 (6.3)	57.7 (5.9)	0.002
BMI, mean (SD), kg/m^2	29.0 (2.9)	28.6 (3.3)	0.33
WC, mean (SD), cm	98.5 (10.0)	104.0 (10.1)	<0.001
Fat mass, mean (SD), kg	56.0 (7.2)	56.8 (7.9)	0.465
Percentage fat, mean (SD), %	27.7 (3.8)	29.4 (4.9)	0.007
Hypertension
SBP, mean (SD), mmHg	133.8 (14.5)	138.4 (10.3)	0.009
DBP, mean (SD), mmHg	86.0 (7.9)	86.6 (8.3)	0.569
Glucose
Fasting glucose, mean (SD), mmol/L	6.3 (0.5)	7.6 (1.8)	<0.001
Lipid profile
Cholesterol	6.1 (1.1)	5.9 (1.2)	0.235
HDL, mean (SD), mmol/L	1.6 (0.4)	1.4 (0.5)	0.001
LDL, mean (SD), mmol/L	3.5 (0.8)	3.4 (0.9)	0.262
TG, mean (SD), mmol/L	1.6 (0.04)	2.3 (1.3)	<0.001
HbA1C, mean (SD), %	5.8 (0.6)	7.4 (1.6)	<0.001
FGF-21 mean (range) pg/ml	285.3 (122.9–811.0)	372.1 (100.0–810.6)	<0.001

SD = standard deviation.