Comparable Enhanced Prothrombogenesis in Simple Central Obesity and Metabolic Syndrome

Table 2

Comparison of fibrinolysis biomarkers concentration between groups in all subjects and according to gender.

Biomarker	MS ()	COB ()	NC ()	value^1 (MS versus NC)	value^2 (COB versus NC)	value^3 (MS versus COB)
All subjects
tPA (ng/ml)	6.12 ± 5.97	4.40 ± 4.39	2.92 ± 2.20
PAI-1 (ng/ml)	70.95 ± 59.85	57.82 ± 49.22	43.74 ± 30.65
Males
tPA (ng/ml)	6.38 ± 6.10	4.78 ± 4.31	2.94 ± 1.90			NS
PAI-1 (ng/ml)	83.61 ± 76.04	62.65 ± 43.28	45.37 ± 33.76		NS	NS
Females
tPA (ng/ml)	5.97 ± 5.92	4.18 ± 4.43	2.90 ± 2.33
PAI-1 (ng/ml)	64.07 ± 47.79	55.95 ± 51.40	42.74 ± 28.87		NS	NS

Data are expressed as mean ± SD. ; NS: not significant; MS: metabolic syndrome; COB: simple central obesity; NC: normal controls; tPA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor.