Journal of Obesity

Clinical Study

Accuracy of Longitudinal Assessment of Visceral Adipose Tissue by Dual-Energy X-Ray Absorptiometry in Children with Obesity

Table 3

Univariate and multiple linear regression illustrating the relationship between absolute and relative changes in VAT CSA, volume, and area measured by MRI (gold standard) and DXA in children with obesity following an intervention.


B	Variable	r value	R² value	B (95% CI)	SE	value

Absolute Δ MRI-VAT CSA
Model 1	Absolute Δ DXA-VAT CSA	0.27	0.07	0.302 (−0.148–0.752)	0.218	0.179
Model 2						0.140
	Absolute Δ body fat %	0.33	0.11	2.729 (−1.014–6.471)	1.813	0.145
	Absolute Δ DXA-VAT CSA	0.39	0.15	0.244 (−0.205–0.693)	0.218	0.272

Relative Δ MRI-VAT CSA
Model 3	Relative Δ DXA-VAT CSA	0.36	0.13	0.569 (−0.030–1.168)	0.291	0.062
Model 4						0.041
	Relative Δ body fat %	0.39	0.15	1.910 (−0.314–4.134)	1.078	0.089
	Relative Δ DXA-VAT CSA	0.48	0.23	0.461 (−0.129–1.051)	0.286	0.120

Absolute Δ MRI-VAT volume
Model 5	Absolute Δ DXA-VAT volume	0.26	0.07	0.254 (−0.137–0.646)	0.190	0.193
Model 6						0.141
	Absolute Δ body fat %	0.33	0.11	12.607 (−4.275–29.489)	8.180	0.136
	Absolute Δ DXA-VAT volume	0.39	0.15	0.199 (−0.188–0.587)	0.188	0.299

Relative Δ MRI-VAT volume
Model 7	Relative Δ DXA-VAT volume	0.35	0.13	0.539 (−0.047–1.126)	0.285	0.070
Model 8						0.065
	Relative Δ body fat %	0.35	0.12	1.649 (−0.563–3.860)	1.072	0.137
	Relative Δ DXA-VAT volume	0.45	0.20	0.443 (−0.143–1.030)	0.284	0.132

Absolute Δ MRI-VAT mass
Model 9	Absolute Δ DXA-VAT mass	0.25	0.07	0.234 (−0.132–0.600)	0.178	0.200
Model 10						0.150
	Absolute Δ body fat %	0.33	0.11	11.239 (−4.075–26.552)	7.420	0.143
	Absolute Δ DXA-VAT mass	0.38	0.15	0.176 (−0.189–0.541)	0.177	0.329

Relative Δ MRI-VAT mass
Model 11	Relative Δ DXA-VAT mass	0.35	0.12	0.507 (−0.049–1.062)	0.270	0.072
Model 12						0.069
	Relative Δ body fat %	0.35	0.12	1.627 (−0.600–3.855)	1.079	0.145
	Relative Δ DXA-VAT mass	0.45	0.20	0.409 (−0.150–0.968)	0.271	0.144

SE, standard error; MRI, magnetic resonance imaging; DXA, dual-energy X-ray absorptiometry; VAT, visceral adipose tissue; CSA, cross-sectional area. Models 1, 5, and 9 describe linear regression results for absolute change in MRI-VAT where corresponding DXA-VAT outcomes were entered as dependent variables. Models 3, 7, and 11 describe linear regression results for relative change in MRI-VAT where corresponding DXA-VAT outcomes were entered as dependent variables. Models 2, 4, 6, 8, 10, and 12 describe multiple regression results for the aforementioned models, accounting for body fat %.