Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study
Table 3
Clinicopathologic characteristics of breast cancer patients by BMI category (N = 348).
Characteristic
Normal weight (n = 64)
Overweight (n = 118)
Obese (n = 166)
value
Age at diagnosisa (years)
43.73 ± 9.23
51.83 ± 11.19
53.16 ± 10.29
<0.001
BMIa (kg/m2)
22.25 ± 2.24
27.76 ± 1.39
33.57 ± 4.12
<0.001
Menopausal status
<0.001
Premenopausal
43 (67.2)
52 (44.1)
58 (34.9)
Postmenopausal
21 (32.8)
66 (55.9)
108 (65.1)
Histologic type
0.191
Invasive ductal carcinoma
56 (87.5)
90 (76.3)
131 (78.9)
Other
8 (12.5)
28 (23.7)
35 (21.1)
Tumor stage
0.248
Early (I/II)
38 (59.4)
68 (57.6)
82 (49.4)
Advanced (III/IV)
26 (40.6)
50 (42.4)
84 (50.6)
Tumor grade
0.003
I and II
28 (43.8)
71 (60.2)
67 (40.4)
III
36 (56.3)
47 (39.8)
99 (59.6)
LVI
0.458
Identified
49 (76.6)
82 (69.5)
125 (75.3)
Not identified
15 (23.4)
36 (30.5)
41 (24.7)
aMean ± SD, one-way ANOVA test. Data are presented as n (%), unless otherwise specified. Statistical significance at . BMI, body mass index; LVI, lymphovascular invasion. Other histologic subtypes included were invasive lobular carcinoma (ILC), ductal carcinoma in situ (DCIS), and mixed invasive ductal and lobular carcinoma.
