Research Article

Dilated Blood and Lymphatic Microvessels, Angiogenesis, Increased Macrophages, and Adipocyte Hypertrophy in Lipedema Thigh Skin and Fat Tissue

Figure 3

Number of blood vessels counted in the thigh skin of Non-Obese and Obese participants with and without lipedema (controls). (A, B) Immunohistochemistry of smooth muscle actin (SMA) positive vessels in the papillary dermal layer of lipedema leg skin (arrows). Note large lymphatic vessels in B (arrowheads) (scale bar 100 µm). (C) Box and whisker plots representing the blood vessel count in groups. Non-Obese group (Control ; Lipedema ); Obese group (Control , Lipedema ). (, ).