Research Article
Could Obesity be a Triggering Factor for Endometrial Tubal Metaplasia to be a Precancerous Lesion?
Table 3
Comparison between the three studied groups according to study markers.
| | Group 1 (n = 57) | Group 2 (n = 57) | Group 3 (n = 68) | χ2 | |
| PAX-2 | Negative | 23 (40.4%) | 5 (8.8%) | 57 (83.8%) | 71.515 | <0.001 | Positive | 34 (59.6%) | 52 (91.2%) | 11 (16.2%) |
| PAX-2 loss score | 1 | 23 (40.4%) | 5 (8.8%) | 31 (45.6%) | 27.376 | <0.001 | 2 | 15 (26.3%) | 24 (42.1%) | 26 (38.2%) | 3 | 19 (33.3%) | 28 (49.1%) | 11 (16.2%) |
| H-TERT | Negative | 36 (63.2%) | 53 (93%) | 10 (14.7%) | 79.158 | <0.001 | Positive | 21 (36.8%) | 4 (7%) | 58 (85.3%) |
| H-TERT score | 0 | 36 (63.2%) | 53 (93%) | 10 (14.7%) | 103.941 | <0.001 | 1 | 1 (1.8%) | 4 (7%) | 3 (4.4%) | 2 | 12 (21.1%) | 0 (0%) | 25 (36.8%) | 3 | 8 (14%) | 0 (0%) | 30 (44.1%) |
| P16 | Negative | 34 (59.6%) | 50 (87.7%) | 45 (66.2%) | 12.043 | 0.002 | Positive | 23 (40.4%) | 7 (12.3%) | 23 (33.8%) |
| P16 score | 0 | 34 (59.6%) | 50 (87.7%) | 46 (67.6%) | 19.369 | 0.001 | 1 | 8 (14%) | 7 (12.3%) | 13 (19.1%) | 2 | 15 (26.3%) | 0 (0%) | 9 (13.2%) |
| Ki67 | Negative | 2 (3.5%) | 10 (17.5%) | 0 (0%) | 15.250 | <0.001 | Positive | 55 (96.5%) | 47 (82.5%) | 68 (100%) |
| ki67 score | 0 | 2 (3.5%) | 10 (17.5%) | 0 (0%) | 123.287 | <0.001 | 1 | 16 (28.1%) | 34 (59.6%) | 0 (0%) | 2 | 17 (29.8%) | 13 (22.8%) | 16 (23.5%) | 3 | 22 (38.6%) | 0 (0%) | 52 (76.5%) |
| P53 | Negative | 31 (54.4%) | 46 (80.7%) | 35 (51.5%) | 13.529 | 0.001 | Positive | 26 (45.6%) | 11 (19.3%) | 33 (48.5%) |
| P53 score | 0 | 31 (54.4%) | 46 (80.7%) | 35 (51.5%) | 25.634 | <0.001 | 1 | 6 (10.5%) | 11 (19.3%) | 13 (19.1%) | 2 | 12 (21.1%) | 0 (0%) | 13 (19.1%) | 3 | 8 (14%) | 0 (0%) | 7 (10.3%) |
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χ2: chi-square test. : value for comparing between the studied groups. Statistically significant at . |