Research Article

Could Obesity be a Triggering Factor for Endometrial Tubal Metaplasia to be a Precancerous Lesion?

Table 3

Comparison between the three studied groups according to study markers.

Group 1 (n = 57)Group 2 (n = 57)Group 3 (n = 68)χ2

PAX-2
 Negative23 (40.4%)5 (8.8%)57 (83.8%)71.515<0.001
 Positive34 (59.6%)52 (91.2%)11 (16.2%)

PAX-2 loss score
 123 (40.4%)5 (8.8%)31 (45.6%)27.376<0.001
 215 (26.3%)24 (42.1%)26 (38.2%)
 319 (33.3%)28 (49.1%)11 (16.2%)

H-TERT
 Negative36 (63.2%)53 (93%)10 (14.7%)79.158<0.001
 Positive21 (36.8%)4 (7%)58 (85.3%)

H-TERT score
 036 (63.2%)53 (93%)10 (14.7%)103.941<0.001
 11 (1.8%)4 (7%)3 (4.4%)
 212 (21.1%)0 (0%)25 (36.8%)
 38 (14%)0 (0%)30 (44.1%)

P16
 Negative34 (59.6%)50 (87.7%)45 (66.2%)12.0430.002
 Positive23 (40.4%)7 (12.3%)23 (33.8%)

P16 score
 034 (59.6%)50 (87.7%)46 (67.6%)19.3690.001
 18 (14%)7 (12.3%)13 (19.1%)
 215 (26.3%)0 (0%)9 (13.2%)

Ki67
 Negative2 (3.5%)10 (17.5%)0 (0%)15.250<0.001
 Positive55 (96.5%)47 (82.5%)68 (100%)

ki67 score
 02 (3.5%)10 (17.5%)0 (0%)123.287<0.001
 116 (28.1%)34 (59.6%)0 (0%)
 217 (29.8%)13 (22.8%)16 (23.5%)
 322 (38.6%)0 (0%)52 (76.5%)

P53
 Negative31 (54.4%)46 (80.7%)35 (51.5%)13.5290.001
 Positive26 (45.6%)11 (19.3%)33 (48.5%)

P53 score
 031 (54.4%)46 (80.7%)35 (51.5%)25.634<0.001
 16 (10.5%)11 (19.3%)13 (19.1%)
 212 (21.1%)0 (0%)13 (19.1%)
 38 (14%)0 (0%)7 (10.3%)

χ2: chi-square test. : value for comparing between the studied groups. Statistically significant at .