Research Article
Could Obesity be a Triggering Factor for Endometrial Tubal Metaplasia to be a Precancerous Lesion?
Table 5
Relation between serum estradiol level and other parameters in group 1 (n = 57).
| | | Estradiol level | Test of sig. | | | ≤300 (n = 37) | >300 (n = 20) |
| | Age (years) | | Mean ± SD | 44.6 ± 11.6 | 58 ± 13 | t = 3.961 | <0.001 | | Median (min.–max.) | 39 (28–68) | 64.5 (37–72) |
| | Menopausal status | | Premenopausal | 26 (70.3%) | 6 (30%) | χ2 = 8.550 | 0.003 | | Postmenopausal | 11 (29.7%) | 14 (70%) |
| | Oral contraceptive history | | Negative | 22 (59.5%) | 7 (35%) | χ2 = 3.108 | 0.078 | | Positive | 15 (40.5%) | 13 (65%) |
| | PAX-2 | | Negative | 5 (13.5%) | 18 (90%) | χ2 = 31.555 | <0.001 | | Positive | 32 (86.5%) | 2 (10%) |
| | H-TERT | | Negative | 33 (89.2%) | 3 (15%) | χ2 = 30.709 | <0.001 | | Positive | 4 (10.8%) | 17 (85%) |
| | P16 | | Negative | 30 (81.1%) | 4 (20%) | χ2 = 20.124 | <0.001 | | Positive | 7 (18.9%) | 16 (80%) |
| | Ki67 | | Negative | 2 (5.4%) | 0 (0%) | χ2 = 1.120 | 0.536 | | Positive | 35 (94.6%) | 20 (100%) |
| | P53 | | Negative | 29 (78.4%) | 2 (10%) | χ2 = 24.469 | <0.001 | | Positive | 8 (21.6%) | 18 (90%) |
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χ2: chi-square test; t: Student’s t-test. : value for association between atypia and different markers. Statistically significant at . |
