Research Article
Could Obesity be a Triggering Factor for Endometrial Tubal Metaplasia to be a Precancerous Lesion?
Table 6
Relation between histologic atypia and other parameters in group 1 (n = 57).
| | | Histologic atypia | Test of sig. | | | No atypia (n = 32) | Atypia (n = 25) |
| | Age (years) | | Mean ± SD | 51 ± 13.8 | 47.2 ± 13.3 | t = 1.039 | 0.303 | | Median (min.–max.) | 49.5 (28–72) | 41 (33–72) |
| | Menopausal status | | Premenopausal | 16 (50%) | 16 (64%) | χ2 = 1.117 | 0.291 | | Postmenopausal | 16 (50%) | 9 (36%) |
| | Oral contraceptive history | | Negative | 16 (50%) | 13 (52%) | χ2 = 0.022 | 0.881 | | Positive | 16 (50%) | 12 (48%) |
| | PAX-2 | | Negative | 13 (40.6%) | 10 (40%) | χ2 = 0.002 | 0.962 | | Positive | 19 (59.4%) | 15 (60%) |
| | H-TERT | | Negative | 19 (59.4%) | 17 (68%) | χ2 = 0.449 | 0.503 | | Positive | 13 (40.6%) | 8 (32%) |
| | P16 | | Negative | 20 (62.5%) | 14 (56%) | χ2 = 0.246 | 0.620 | | Positive | 12 (37.5%) | 11 (44%) |
| | Ki67 | | Negative | 2 (6.3%) | 0 (0%) | χ2 = 1.619 | 0.499 | | Positive | 30 (93.8%) | 25 (100%) |
| | P53 | | Negative | 17 (53.1%) | 14 (56%) | χ2 = 0.047 | 0.829 | | Positive | 15 (46.9%) | 11 (44%) |
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χ2: chi-square test; t: Student’s t-test. : value for association between atypia and different markers. Statistically significant at . |
