Research Article

Weight Change and Its Association with Cardiometabolic Risk Markers in Overweight and Obese Women

Table 1

Baseline characteristics of participants in the control and intervention group stratified by weight change category after 12 months.

Cardiometabolic risk markersControlIntervention
>2% gain±2% maintain>2–<5% loss5–20% loss value>2% gain±2% maintain>2–<5% loss5–20% loss value

N3543191727582717
Age, year41.1742.2643.7441.000.66740.7442.9542.2243.290.640
(8.09)(7.80)(7.12)(9.31)(8.83)(8.12)(5.85)(8.59)
Weight, kg71.9771.5476.3070.310.33776.3577.0872.9479.830.235
(12.99)(9.25)(12.44)(10.99)(11.54)(9.88)(10.96)(15.31)
BMI, kg/m230.8330.7832.2329.200.17931.7832.0430.1232.830.133
(4.44)(3.52)(4.59)(3.91)(3.99)(4.12)(3.86)(4.56)
WC, cm90.5393.0795.9790.660.16096.0894.6493.0498.860.289
(10.34)(7.32)(11.64)(6.91)(10.78)(9.47)(9.23)(12.73)
FPG, mmol/L5.505.486.165.720.3285.555.425.776.210.474
(0.64)(0.85)(1.66)(1.11)(0.75)(0.60)(2.20)(2.48)
Insulin, μU/mL7.929.8710.379.770.35110.619.179.1515.030.043
(1.61)(1.66)(1.78)(1.94)(1.83)(1.90)(1.89)(1.64)
HOMA-IR1.942.372.932.460.2292.832.192.264.020.019
(1.70)(1.75)(2.01)(2.12)(2.03)(2.00)(1.95)(1.92)
TC, mmol/L5.565.726.055.500.3385.745.625.335.660.398§
(1.10)(1.16)(0.82)(1.15)(1.06)(0.86)(0.95)(1.46)
LDL-C, mmol/L4.474.644.944.350.5274.634.504.134.420.394
(1.29)(1.42)(1.28)(1.20)(1.43)(0.88)(1.00)(1.41)
HDL-C, mmol/L1.361.371.421.430.6991.321.331.301.260.674
(0.26)(0.22)(0.21)(0.23)(0.25)(0.21)(0.24)(0.26)
Triglycerides, mmol/L1.211.361.701.210.0521.471.231.381.520.283
(0.71)(0.63)(0.56)(0.62)(0.66)(0.45)(0.86)(0.95)
TNF-α, μg/mL10.8111.3610.658.880.29411.5910.5310.4011.410.459
(2.52)(3.57)(3.78)(3.68)(3.12)(2.56)(1.84)(3.83)
Adiponectin, μg/mL6.276.417.2013.740.09210.275.814.294.02<0.001
(1.54)(2.36)(3.15)(2.48)(1.99)(2.03)(1.95)(1.41)
Hs-CRP, mg/L2.373.164.173.990.3415.883.641.773.680.002
(2.12)(3.13)(1.81)(2.33)(3.64)(2.29)(3.17)(2.03)

Note. Data were presented as mean ± SD. value indicates the statistical significance of the ANOVA test for comparison between weight change categories. Values in bold indicate statistical significance at .