Review Article
Lipid-Induced Mechanisms of Metabolic Syndrome
Table 1
Family of FFARs and their ligands.
| | Free fatty acid receptors | Expression | Ligand |
| | FFAR1 (GPR40) | Nerve cells, immune cells, adipocytes, pancreatic β-cells, smooth muscle cells of respiratory tract | Medium-chain fatty acids and long-chain fatty acids | | FFAR2 (GPR43) | Nerve cells, immune cells, adipocytes, pancreatic β-cells, intestinal epithelial cells, airway epithelial cells | Short-chain fatty acids | | FFAR3 (GPR41) | Nerve cells, immune cells, adipocytes, pancreatic β-cells, intestinal epithelial cells, airway epithelial cells | Short-chain fatty acids | | FFAR4 (GPR120) | Nerve cells, adipocytes, immune cells, pancreatic β-cells, cells of the intestine | Medium-chain fatty acids and long-chain fatty acids |
|
|
