Research Article

The Ventilatory and Diffusion Dysfunctions in Obese Patients with and without Obstructive Sleep Apnea-Hypopnea Syndrome

Table 2

Respiratory functional data of the two obese groups.

Control group (n = 25)OSAS group (n = 23)Total sample (n = 48)

FEV1 (L)3.26 ± 0.702.59 ± 0.752.95 ± 0.790.005
FEV1 (%)99 ± 1283 ± 1591 ± 16<0.001
FEF50% (L/s)4.45 ± 1.143.72 ± 1.214.11 ± 1.210.057
FEF50% (%)98 ± 2385 ± 2692 ± 250.057
FEF25% (L/s)1.43 ± 0.501.20 ± 0.571.33 ± 0.540.217
FEF25% (%)74 ± 2269 ± 3572 ± 290.412
MMEF (L/s)3.51 ± 0.902.99 ± 0.933.26 ± 0.940.062
MMEF (%)89 ± 1979 ± 2684 ± 230.138
SVC (L)3.98 ± 0.903.25 ± 0.963.64 ± 0.990.017
SVC (%)98 ± 1483 ± 1291 ± 16<0.001
FVC (L)4.00 ± 0.943.14 ± 1.023.60 ± 1.060.006
FVC (%)100 ± 1383 ± 1492 ± 16<0.001
FEV1/FVC (%)82 ± 6.79 ± 981 ± 80.412
RV (L)1.66 ± 0.501.65 ± 0.721.66 ± 0.610.525
RV (%)90 ± 2284 ± 3287 ± 270.241
TLC (L)5.65±1.214.76±1.285.23±1.310.018
TLC (%)93±1479±1287±15<0.0001
DLCO (mmol/KPa/min)10.70±2.408.70±2.409.80±2.600.008
DLCO (%)112±2093±22103±230.001
FeNO (ppb)18.40±9.2031.30±13.6024.85±11.40<0.0001

DLCO, carbon monoxide transfer capacity; FEFx%, forced expiratory flow at x% of FVC; FeNO, fraction of exhaled nitric oxide; FEV1, forced expiratory volume at the first second; FVC, forced vital capacity; MMEF, maximal mid-expiratory flow; ns, not significant difference; RV, residual volume; SVC, slow vital capacity; TLC, total lung capacity; %, percentage of predicted value; , comparison between controls and OSAS groups by the Mann–Whitney U test.